COVID-19 vaccine trials resume in UK

Clinical trials for Covid-19 vaccine being developed by Irish-led Oxford University researchers to resume

Sputnik V Covid vaccine, which is developed by Gamaleya Research Institute of Epidemiology and Microbiology under the Russian Health Ministry, may be granted permission to release a batch of its vaccine for civilian use, the institute's deputy director for research, associate member of the Russian Academy of Sciences, Denis Logunov said earlier, according to a report.

Charlotte Summers, lecturer in intensive care medicine at Cambridge University, welcomed the resumption of the Oxford trial and said the researchers had shown their commitment "to putting safety at the heart of their development program".

AstraZeneca and the University of Oxford, as the trial sponsor, said that they can not disclose further medical information but confirmed that independent investigations concluded that the trials were safe to restart.

"On Sunday, our standard review process triggered a study pause to vaccination across all of our global trials to allow the review of safety data by an independent safety review committee, and the national regulators".

After the pause, AstraZeneca had said it remained hopeful that the vaccine could still be available "by the end of this year, early next year".

Dr Chiu will work with Imperial's Professor Robin Shattock and Oxford's Professor Sarah Gilbert to assess the vaccines by delivering them to a small group of healthy volunteers as an aerosol - similar to how inhaled asthma medications are delivered.

"The UK committee has concluded its investigations and recommended to the MHRA that trials in the UK are safe to resume", added AstraZeneca.

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In fact, Ad5-nCoV became China's first Covid-19 vaccine to be granted invention patent by the authorities.

All three are not expected to be ready for public use until 2022.

AstraZeneca previously also received permission to conduct the third stage of clinical trials of the AZD1222 vaccine in Russian Federation, follows from the state register of clinical trials. Extolling the benefits of the "Sputnik-V" vaccine, he said that as the vaccine was based on ' human adenoviral vectors", it was proven to be "safe and effective'. Volunteers from some of the worst affected countries - Britain, Brazil, South Africa and the USA - are taking part in the trial.

In comparison, Oxford's vaccine uses a harmless virus - a chimpanzee cold virus, engineered so it can't spread - to carry the coronavirus' spike protein into the body, which should trigger an immune response.

Scientists and others around the world, including experts at the World Health Organization, have sought to keep a lid on expectations of an imminent breakthrough for coronavirus vaccines, stressing that vaccine trials are rarely straightforward.

Business Secretary Alok Sharma said: "I am immensely proud that the United Kingdom is home to two of the most promising Covid-19 vaccine candidates, backed by over £130million of government funding to speed up the search for a vaccine and end the pandemic sooner".

"It's really one of the safety valves that you have on clinical trials such as this", he told "CBS This Morning".

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